Posts tagged Niacin

Multiple sclerosis nutritional supplements: Where to find them

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Multiple sclerosis nutritional supplements, necessary for applying the protocol

Multiple sclerosis nutritional supplements that you use must be of high quality. This page contains my personal suggestions concerning the vitamins and supplements (in tablets, powder or liquid form)  for multiple sclerosis according Dr Klenner's protocol for ms that you can purchase through the internet. All oral Multiple sclerosis nutritional supplements referred below have been used by me and many other patients.

The prices are the lowest possible. Every supplement is exactly what the protocol asks for, as it concerns the type and the ingredients it should contain.  In case you need help, please let me know in mymultiple [at] gmail [dot] com.

Buying multiple Sclerosis nutritional supplements by using the links above you get cewrtain discouints while you are helping the website develope.

After a broad research I have come to the following suggestion. BUYING MULTIPLE SCLEROSIS NUTRITIONAL SUPPLEMENTS BY USING THE LINKS BELOW YOU EARN IMPORTANT DISCOUNTS AND ALSO HELP THIS WEBSITE!

* Using iherb.com links you may save $10 on purchases of $40 or more, or $5 if the order is less than $40.

MAIN VITAMINS OF THE PROTOCOL

  •  Vitamin C – As Calcium Ascorbate (non – acidic form)
"Our Best Quality Choice":

NutriBiotic, Calcium Ascorbate, Crystalline Powder, 16 oz (454 g)

I use this product myself. It is dissolved into a glass of water or your favourite juice and is 100% stomach friendly. It is like drinking your water or juice with vitamin C in it with slightly changed taste. It is easy to take when sick in large doses since it's potency is 5 grams per teaspoon! It is a pharmaceutical product with absolutely no fillers or additives.

Type: Calcium Ascorbate

Potency/Dosage: 5grams/Teaspoonful

Purchase from: HERE

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OTHER CHOICES:

Ultra C-400 by MegaFood – 60 Tablets

Mega Food is maybe the only brand which creates vitamins based on foods. This product contains a variety of powerful antioxidants from whole foods and herbs. Oranges, broccoli, blueberry and carrot are a few. These ingredients, help to improve the strength of your immune system and maintain a healthy inflammatory response. It is naturally buffered and thus stomach friendly. 

It is good to use it with the product above from time to time for even better reasult.

Type: Naturally buffered Vitamin C

Potency/Dosage: 400 mg per tablet

Purchase from: Here

Other Ingredients: Plant Cellulose and Vegetable Lubricant

Ester C 1000 mg with Citrus Bioflavonoids180 VTabs

If you prefer tablets this is a good choice but not for long term use in my opinion. The reason is it contains additives (vegetable magnesium stearate). the good thing is it contains bioflavonoids which help enhance the absorption.

Type: Calcium Ascorbate

Potency/Dosage: 1000 mg, Until bowel tolerance

Purchase from: HERE

Other Ingredients: Gelatin, Vegetable Magnesium Stearate.

Note: Ester – C can be combined with the above mentioned Buffered C (Best quality choice).

  • Vitamin D
"Our Best Quality Choice":

Multiple Sclerosis Vitamin D3Vitamin D3 2000 IU – 120 Softgels

This Vitamin D3 softgel is in a highly-absorbable liquid softgel form. Vitamin D3 is normally obtained from the diet or produced by the skin from the ultraviolet energy of the sun. However, it is not abundant in food. As more people avoid sun exposure, ALWAYS USE WITH CALCIUM, MAGNESIUM AND VITAMIN K2.

Type: Cholecalciferol

Potency: 2000IU/softgel

Purchase from: HERE

Other Ingredients: Rice Bran Oil and Softgel Capsule (gelatin, glycerin and water).

  • Vitamin Ε

"Our Best Quality Choice":

Multiple Sclerosis Nutritional Supplements - Vitamin EType: UNIQUE E® Mixed Tocopherols Concentrate

Potency: Contains the Highest Concentrations of PURE Vitamin E available • 700mg of the natural vitamin E complex of molecules • High d-gamma tocopherol, with a minimum of 300mg per capsule • 400 I.U. of alpha-tocopherol (268mg) per capsule.

Contains NO SOY, or other OIL FILLER additives or allergens which can turn rancid and cause harmful free radical damage even in sealed gel capsules. Also contains NO ALLERGY CAUSING PRESERVATIVES, COLORS OR FLAVORINGS.

Purchase from: HERE

Other Ingredients: Gelatin, glycerin, water.

  • B Vitamins
"Our Best Quality Choice":

Vitamin B-100 Sustained Release – 100 Tabs

Vitamin B-100 Sustained Release from Now contain many B-Vitamins, Choline and Inositol, which encourage a healthier nervous system. Because B-Vitamins dissolve in water, they need to be replenished daily; this sustained release formula is great and helps the effects of the B-Vitamins to last longer by releasing them throughout a prolonged period of time. 

Type: All B Vitamins

Potency/Dosage: Some are 100mg (like B1, B2 etc) some others like folic Acid come in 400mcg / 1 tablet daily.

Purchase from: HERE

Omega-3 Factors is a pharmaceutical grade fish oil concentrate providing one of the highest potencies of EPA and DHA available. Stringent quality control standards ensure this highly purified fish oil concentrate is free from toxic environmental contaminants and heavy metals like mercury.

Potency/Dosage: 1 to 3 softgels daily with food

Purchase from: HERE

"Our Best Quality Choice":

Type: Ionic Form

Potency: 10mg per tablespoon – Take one tablespoon daily away from food or other vitamins. Increase if needed.

Other Ingredients: None

Purchase from: HERE

Note: Large doses are used in solid supplements because most of the mineral is not absorbed.

OTHER CHOICES

Calcium Citrate is an optimal calcium supplement formulated to exacting specifications. Our Calcium is complexed with citric acid for enhanced solubility and contains no other ingredients.

NOTES: Free of: soy, corn, wheat, gluten, sugar, yeast, milk, salt.

100% VEGETARIAN.

"Our Best Quality Choice":

Magnesium is a mineral that is critical for energy production and metabolism, muscle contraction, nerve impulse transmission, and bone mineralization. It is a required cofactor for an estimated 300 enzymes. Among the reactions catalyzed by these enzymes are fatty acid synthesis, protein synthesis, and glucose metabolism. Magnesium status is also important for regulation of calcium balance through its effects on the parathyroid gland. NOW Magnesium Citrate Powder is a highly bioavailable form of magnesium and contains no excipients or fillers.

Type: Powder

Potency: 450mg per teaspoon. Take one teaspoon daily away from Calcium. At bedtime it may help for a better sleep.

Other Ingredients: None

Purchase from: HERE

OTHER CHOICES

Type: Ionic

Potency: 80mg per tablespoon – Take one tablespoon daily usually at nights. Increase if needed.

Other Ingredients: None

Purchase from: HERE

Note: Large doses are used in solid supplements because most of the mineral is not absorbed.

Type: Nicotinic Acid

Potency: 100mg

Purchase from: HERE

  • Digestive Enzymes
"Our Best Quality Choice":

Multiple Sclerosis Nutritional SupplementsType: Enzymedica's Digestive blends for good digestion and therapeutic use.

Potency: Depends on what you or your healthcare practitioner suggests. One very good choice is ViraStop (60 or 120 capsules) or for a stronger use ViraStop 2x. This product helps digest protein and supports immune function and provides you with 150,000 units of activity (double if ViraStop 2x is used). Protease is able to dissolve almost all proteins as long as they are not components of living cells. Viruses are cell parasites consisting of nucleic acids covered by a protein film. Parasites, fungal forms and bacteria are made up of protein. Virastop contains eight different proteases which can break down undigested protein, cellular debris, and toxins in the blood, sparing the immune system this task. The immune system can then concentrate its full action on the invasion.

Depending on your condition you may choose other types which include other blends (amylase, lipase etc) also but breaking down protein in many levels is a must for your nutrition.

Other Ingredients: None

Purchase from: Here

Dosage: For maintenance, take one capsule two times a day, one hour before or two hours after a meal (empty stomach). For Therapeutic effect Virastop should be taken three to four times a day. More may be taken if needed.

Note: We suggest visiting Enzymedica's official website and taKe the on line free educational course on enzymes.

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Other Choices:

Type: Organika Full Spectrum – Plant Based

Potency: 500mg

Purchase from: USA

Dosage: 2 capsules per meal. In case you have bloating reduce the dose to one capsule or don't take them in every meal. If you are over 30 you should consider trying digestive enzymes. You should also eat many raw foods like vegetables and fruits which contain enzymes.

OTHER PRODUCTS THAT MAY BE USEFUL (They are NOT included in the main protocol but they can be very useful. If you need more information, you can come in touch):

Type: Selenomethionine

Potency: 400mcg – Take one daily or as directed by your health care practitioner

Purchase from: USA

Selenium can be found in different types that may contain yeast, gluten etc. I think that the link suggested is a very reliable source.

Type: Beta Carotene

Purchase from: USA

Potency: 25000IU

Alternatives: Beta Carotene with mixed Carotenoids

  • Probiotics

Purchase from: Europe, USA

Note: Keep refrigerated even if it is not mentioned on the label. More than two friendly bacteria should be contained.

  • Methylcobalamine – Sublingual use (Choose from the links below according to potency)

Type: Mehylcobalamine

Potency: 1-5 mg

Purchase from: USA (1mg, 5mg or Europe (1mg)

Dosage: 2-5mg daily

"Our Best Quality Choice":

Type: Liquid

Potency: See the label

Other Ingredients: Kosher certified vegetable glycerin, purified water (pH neutral), Trace Minerals.

Purchase from: USA

Dosage: 1/4 tablespoon (2 droperfuls)

OR

Type: Liquid

Potency: See the label

Other Ingredients: certified organic grain alcohol (63-73%), distilled water & Turmeric extractives.

Purchase from: USA – iherb

Dosage: Two to five times per day take 30 to 40 drops in a little water.

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500mg, 1-2 tablets daily

Purchase from: Europe

Note: Strong antioxidant. There have been studies about MS.

 

  • Co-enzyme CoQ10 – Important for the production of energy in all cells. Plays an antioxidant role as well.

Type: Ubiquinol.

Potency/Dosage: 100mg, Take two softgels daily

Purchase from: USA

Note: This is the final type the co-enzyme is transformed in order to be assimilated. This ability is reduced as we grow older; this is why co-enzyme is better to be taken in this active form.

 

Potency/Dosage: 500mg, Start with three tablets (morning-noon-night) with food. Raise the dose gradually.

Purchase from: USA

Note: There is no toxicity because it is an algae, that is food. Helps excrete heavy metals and clean the intestines.

 

  • Zinc (Strengthens the immune system)

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"Our Best Quality Choice":

Type: Ionic

Potency: 3mg per tablespoon – Take one tablespoon daily. Increase if needed.

Other Ingredients: Purified Water

Purchase from: USA, iherb.com

Note: Large doses are used in solid supplements because most of the mineral is not absorbed.

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Other Choices:

Type: Zinc Citrate

Potency/Dosage: 50mg, Suggested dose 1 tablet daily or as directed by your health care practitioner

Purchase from: USA.

Ingredients: Gelatin, microcrystalline cellulose (plant fiber), may contain one or both of the following: magnesium stearate, silica.

 

Type: Calcium Ascorbate

Potency/Dosage: 3gr per teaspoon, You may take at any situation if you have problems until bowel tolerance.

Purchase from: USA

Note: It is exactly the same type as the above mentioned one, but it can be consumed in larger quantities in case it is needed (cold, flu, viral infection etc). Every teaspoon diluted in water equals to 3gr.

Vitamins Fight MS

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(OMNS) New research confirms that niacinamide, also known as vitamin B-3, is a key to the successful treatment of multiple sclerosis and other nerve diseases. [1] Niacinamide, say researchers at Harvard Medical School, “profoundly prevents the degeneration of demyelinated axons and improves the behavioral deficits.”

This is very good news, but it is not at all new news. Over 60 years ago, Canadian physician H.T. Mount began treating multiple sclerosis patients with intravenous B-1 (thiamine) plus intramuscular liver extract, which provides other B-vitamins. He followed the progress of these patients for up to 27 years. The results were excellent and were described in a paper published in the Canadian Medical Association Journal in 1973. [2]

Mount was not alone. Forty years ago, Frederick Robert Klenner, M.D., of North Carolina, was using vitamins B-3 and B-1, along with the rest of the B-complex vitamins, vitamins C and E, and other nutrients including magnesium, calcium and zinc to arrest and reverse multiple sclerosis. [3,4] Klenner’s complete treatment program was originally published as “Treating Multiple Sclerosis Nutritionally,” Cancer Control Journal 2:3, p 16-20.

Drs. Mount and Klenner were persuaded by their clinical observations that multiple sclerosis, myasthenia gravis, and many other neurological disorders were primarily due to nerve cells being starved of nutrients. Each physician tested this theory by giving his patients large, orthomolecular quantities of nutrients. Mount’s and Klenner’s successful cures over decades of medical practice proved their theory was correct. B-complex vitamins, including thiamine as well as niacinamide, are absolutely vital for nerve cell health. Where pathology already exists, unusually large quantities of vitamins are needed to repair damaged nerve cells.

Nutritional therapy is inexpensive, effective and, most important, safe. There is not even one death per year from vitamins. [5]

Vitamin supplementation is not the problem. It is under-nutrition that is the problem. Vitamins are the solution.

Restoring health must be done nutritionally, not pharmacologically. All cells in all persons are made exclusively from what we drink and eat. Not one cell is made out of drugs.

References:

[1] Kaneko S, Wang J, Kaneko M, Yiu G, Hurrell JM, Chitnis T, Khoury SJ, He Z. Protecting axonal degeneration by increasing nicotinamide adenine dinucleotide levels in experimental autoimmune encephalomyelitis models. J Neurosci. 2006 Sep 20;26(38):9794-804.

[2] Mount HT. Multiple sclerosis and other demyelinating diseases. Can Med Assoc J. 1973 Jun 2;108(11):1356-1358.

[3] Frederick R. Klenner. “Response of Peripheral and Central Nerve Pathology to Mega-Doses of the Vitamin B-Complex and Other Metabolites”, Journal of Applied Nutrition, 1973,

[4] Dr. Klenner’s “Clinical Guide to the Use of Vitamin C” (which discusses orthomolecular therapy with all vitamins, not just vitamin C) is now posted in its entirety. It includes a multiple sclerosis protocol, which takes up about five pages. See also: http://www.doctoryourself.com/klennerpaper.html

[5] Watson WA et al. 2003 annual report of the American Association of Poison Control Centers Toxic Exposure Surveillance System. Am J Emerg Med. 2004 Sep;22(5):335-404.

Rigged Trials: Drug Studies Favor The Manufacturer

Orthomolecular Medicine News Service, November 5, 2008

(OMNS, November 5, 2008) If you have often suspected that drug studies are rigged by the pharmaceutical manufacturer, you are right. “Drug studies skewed toward study sponsors,” reported The Washington Post. (1) “Industry-funded research often favors patent-holders, study finds.” Specifically, the American Journal of Psychiatry study authors said, “In 90% of the studies, the reported overall outcome was in favor of the sponsor’s drug. . . On the basis of these contrasting findings in head-to-head trials, it appears that whichever company sponsors the trial produces the better antipsychotic drug.” (2)

Marcia Angell, MD, former editor-in-chief of the New England Journal of Medicine, agrees. “Is there some way (drug) companies can rig clinical trials to make their drugs look better than they are? Unfortunately, the answer is yes. Trials can be rigged in a dozen ways, and it happens all the time.” One “way to load the dice,” she writes, “is to enroll only young subjects in trials, even if the drugs being tested are meant to be used mainly in older people. Because young people generally experience fewer side effects, drugs will look safer.” Another of the “common ways to bias trials is to present only part of the data – the part that makes the product look good – and ignore the rest.” She adds, “The most dramatic form of bias is out-and-out suppression of negative results.” (3)

You will rarely hear academia complain. Why? Because they are aboard the gravy train. Dr. Angell: “Columbia University, which patented the technology used in the manufacture of Epogen and Cerezyme, collected nearly $300 million in royalties” in 17 years. “The patent was based on NIH-funded research.” That means you, the taxpayer, footed the bill. Harvard is in just as deep. In its own Faustian dealings with the drug companies, “a Harvard hospital has a deal that gives Novartis rights to discoveries that lead to new cancer drugs. . . Merck is building a twelve-story research facility next door to Harvard Medical School . . . In Harvard Medical School ’s Dean’s Report for 2003-4, the list of benefactors included about a dozen of the largest drug companies.”

Clearly drug companies are more concerned with profits than with patients. The psychiatric drug market is a very big business. American doctors prescribe $10 billion worth of antipsychotic drugs every single year. The pharmaceutical industry, says Angell, is “primarily a marketing machine to sell drugs of dubious benefit.” Big pharma is “taking us for a ride.” And it is no mere jaunt around the park. Total drug industry worldwide sales are in excess of $500 billion per year, half of which are in North America. Profit margins are typically 20 per cent, so high that “the combined profits for the ten drug companies in the Fortune 500 were more than the profits for all the other 490 businesses put together.”

But more cash does not buy more cures. In fact, said the Washington Post: “When the federal government recently compared a broader range of drugs in typical schizophrenia patients in a lengthy trial, the two medications that stood out were cheaper drugs not under patent.” (1) It gets even more interesting when we broaden our list of treatment options to include nutrition. With the therapeutic use of vitamin supplements, the cost goes down much further, and the success rate goes way up. Orthomolecular (nutritional) therapy, says psychiatrist Abram Hoffer, MD, PhD, is many times more effective than drug therapy. He says that niacin (vitamin B-3) in sufficiently high doses is the most effective, least expensive, and safest treatment for schizophrenia and a number of other very serious mental illnesses. Hoffer and colleagues demonstrated this decades ago when, in the early 1950s, they successfully conducted the very first double-blind, placebo-controlled nutritional studies i! n the history of psychiatry. (4)

Niacin is a clinically proven therapy for serious mental illness, and yet the medical profession has delayed endorsing it for over fifty years. Instead, drug treatments dominate. But drugs are not doing the job. A double-blind study of schizophrenics showed that three-quarters of them stopped taking pharmaceutical medication either because of intolerability or inefficacy. That means that either the drug side effects were unbearable, or the drug just plain did not work. (5)

Perhaps drugs are not the answer because mental illness is not caused by drug deficiency. But much illness, especially mental illness, may indeed be caused by nutrient deficiency or nutrient dependency. Only nutrients can correct this problem. This not only makes sense, it has stood up to clinical trial again and again. (6) Vitamins like niacin are cheap, safe and effective. Modern “wonder drugs” are none of those. But they do make money. Especially when the drug makers control the research, the advertising, and the doctors. No wonder which approach you’ve heard more about.

We’ve all been carefully taught that drugs cure illness, not vitamins. The system is remarkably well-entrenched. 2.3 million Americans per year serve as human subjects for pharmaceutical company drug testing. Pharmaceutical companies set up patient support or advocacy groups to attract specific subjects for their clinical trials. Doctors are paid an average of $7,000 per patient for every patient they enroll in a drug study. Drug companies pay nearly two-thirds of the costs of continuing medical education. While the pharmaceutical industry’s reach into education is bad enough, its grip on research is scandalous. For example: Drug company “publications strategies” have them “sponsor minimal research, prepare journal articles based on it, and pay academic researchers to put their names on those articles.” So bad is it that Dr. Angell wrote an editorial in NEJM (7) entitled “Is Academic Medicine for Sale?” A reader wryly responded, “No. The current owner is very happy with i! t.”

The result? “Bias is now rampant in drug trials. . . (Pharmaceutical) industry-sponsored research was nearly four times as likely to be favorable to the company’s product as NIH-sponsored research.” (3) Remember, “NIH-sponsored” means “taxpayer-funded.” And then, when they need to use a drug, those same taxpayers pay again, and way too much, for the drug they already paid out grant money to develop, in a rigged trial, for a high-profit company.

What a sweet system for the pharmaceutical industry.

References:

(1) Drug studies skewed toward study sponsors. Industry-funded research often favors patent-holders, study finds. Vedantam S. The Washington Post, April 11, 2006. http://www.msnbc.msn.com/id/12275329/from/RS.5/

(2) Heres S, Davis J , Maino K, et al. Why Olanzapine Beats Risperidone, Risperidone Beats Quetiapine, and Quetiapine Beats Olanzapine: An Exploratory Analysis of Head-to-Head Comparison Studies of Second-Generation Antipsychotics. Am J Psychiatry 163:185-194, February 2006. http://ajp.psychiatryonline.org/cgi/content/full/163/2/185

(3) Angell M. The Truth about the Drug Companies. NY: Random House, 2004.

(4) Hoffer A. Healing Schizophrenia. Complementary Vitamin & Drug Treatments. Ontario: CCNM Press (2004). ISBN-10: 1897025084; ISBN-13: 978-1897025086. Also: Vitamin B-3 and Schizophrenia: Discovery, Recovery, Controversy, by Abram Hoffer, MD. Quarry Press, Kingston, Ontario Canada (1998) ISBN 1-55082-079-6. Reviewed at http://www.doctoryourself.com/review_hoffer_B3.html

List of publications by Abram Hoffer: http://www.doctoryourself.com/biblio_hoffer.html

(5) Stroup TS, Lieberman JA, McEvoy JP et al. Effectiveness of olanzapine, quetiapine, risperidone, and ziprasidone in patients with chronic schizophrenia following discontinuation of a previous atypical antipsychotic. Am J Psychiatry. 2006 Apr;163(4):611-22. See also: Stroup TS, McEvoy JP, Swartz MS et al. The National Institute of Mental Health Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE) project: schizophrenia trial design and protocol development. Schizophr Bull. 2003;29(1):15-31.

(6) For free access to peer-reviewed nutrition therapy journal articles: http://orthomolecular.org/library/jom

(7) Angell M. Is academic medicine for sale? N Engl J Med. 2000 May 18;342(20):1516-8.

Orthomolecular medicine uses safe, effective nutritional therapy to fight illness. For more information: http://www.orthomolecular.org

The peer-reviewed Orthomolecular Medicine News Service is a non-profit and non-commercial informational resource.

Editorial Review Board:

Damien Downing, M.D.
Steve Hickey, Ph.D.
Abram Hoffer, M.D., Ph.D.
James A. Jackson, PhD
Bo H. Jonsson, MD, Ph.D
Thomas Levy, M.D., J.D.
Erik Paterson, M.D.
Gert E. Shuitemaker, Ph.D.

Andrew W. Saul, Ph.D., Editor and contact person. Email: omns@orthomolecular.org

To Subscribe at no charge: http://www.orthomolecular.org/subscribe.html

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